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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA1704
All Species:
40.61
Human Site:
S221
Identified Species:
74.44
UniProt:
Q8IXQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXQ4
NP_061029.2
340
38142
S221
D
D
T
S
G
D
R
S
I
W
T
D
T
P
A
Chimpanzee
Pan troglodytes
XP_509661
340
38139
S221
D
D
T
S
G
D
R
S
I
W
T
D
T
P
A
Rhesus Macaque
Macaca mulatta
XP_001094145
344
38614
S225
D
D
T
S
G
D
R
S
I
W
T
D
T
P
A
Dog
Lupus familis
XP_851499
342
38712
S223
D
D
K
S
G
D
R
S
V
W
T
D
T
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZC8
346
38936
S227
D
D
K
S
G
D
R
S
V
W
T
D
T
P
A
Rat
Rattus norvegicus
Q4V893
348
39156
S229
D
D
K
S
G
D
R
S
V
W
T
D
T
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514535
347
38704
S228
E
D
K
S
G
D
R
S
I
W
T
D
T
P
A
Chicken
Gallus gallus
NP_001006270
350
39239
S231
E
D
K
S
G
D
R
S
V
W
T
D
T
P
A
Frog
Xenopus laevis
NP_001089474
337
37926
S218
N
E
K
S
G
D
R
S
I
W
T
D
T
P
A
Zebra Danio
Brachydanio rerio
NP_001003473
405
45367
S285
G
P
E
N
K
D
R
S
I
W
T
D
T
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996214
349
39457
A234
T
P
Q
S
E
A
D
A
A
A
S
G
P
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93591
297
33204
W191
T
S
E
R
D
A
S
W
E
D
A
P
G
A
K
Sea Urchin
Strong. purpuratus
XP_796639
403
45460
S275
R
P
E
E
T
D
R
S
E
W
T
D
T
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.3
91.5
N.A.
89.5
87.3
N.A.
64.2
68.8
63.2
47.1
N.A.
26.9
N.A.
27.6
37.9
Protein Similarity:
100
100
98.5
96.1
N.A.
93.6
93.3
N.A.
75.2
80
75.8
60.2
N.A.
41.5
N.A.
44.7
53.8
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
86.6
80
80
66.6
N.A.
6.6
N.A.
0
60
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
73.3
N.A.
26.6
N.A.
0
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
8
8
8
8
0
0
8
85
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
47
62
0
0
8
85
8
0
0
8
0
85
0
0
0
% D
% Glu:
16
8
24
8
8
0
0
0
16
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
70
0
0
0
0
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
47
0
0
0
0
0
0
% I
% Lys:
0
0
47
0
8
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
24
0
0
0
0
0
0
0
0
0
8
8
85
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
85
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
77
0
0
8
85
0
0
8
0
0
0
8
% S
% Thr:
16
0
24
0
8
0
0
0
0
0
85
0
85
0
0
% T
% Val:
0
0
0
0
0
0
0
0
31
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
85
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _